Phys. Rev. Lett. 81, 4008 - 4011 (1998)

Super-Rough Dynamics on Tumor Growth

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Antonio Brú1 *, Juan Manuel Pastor2, Isabel Fernaud3, Isabel Brú4, Sonia Melle2, and Carolina Berenguer5
1CIEMAT, Avenida Complutense, 22, 28040 Madrid, Spain
2Departamento de Física Fundamental, UNED, c/Senda del Rey s/n, 28040 Madrid, Spain
3Instituto Ramón y Cajal, CSIC, Madrid, Spain
4Hospital SS Ntra. del Prado, Talavera de la Reina, 45600, Spain
5Facultad de Ciencias, Universidad de Alicante, 03690 Alicante, Spain

Featured in Physics News Update Received 22 May 1998

The growth of a cultivated typical brain tumor is studied in this work. The tumor is analyzed both dynamically and morphologically. We have measured its fractal dimension to be df  =  1.21±0.05. From its dynamical behavior we determine the scaling critical exponents of this circular symmetry system which are compatible with the linear molecular beam epitaxy universality class. A very important feature of tumor profiles is that they are super-rough, which constitutes the first ( 1+1)-dimensional experiment in literature with super-roughness. The results obtained from the dynamics study make manifest two very surprising features of tumor growth: Its dynamics is mainly due to contour cells and the tendency of an interface cell to duplicate is a function of the local curvature.


©1998 The American Physical Society

URL: http://link.aps.org/doi/10.1103/PhysRevLett.81.4008
DOI: 10.1103/PhysRevLett.81.4008
PACS: 87.22.As, 47.53.+n, 47.54.+r, 68.35.Ct

* Electronic address: bruno@ciemat.es

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