Phys. Rev. Lett. 94, 018102 (2005) [4 pages]

Scale-Free Brain Functional Networks

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Victor M. Eguíluz1, Dante R. Chialvo2, Guillermo A. Cecchi3, Marwan Baliki2, and A. Vania Apkarian2
1Instituto Mediterráneo de Estudios Avanzados, IMEDEA (CSIC-UIB), E07122 Palma de Mallorca, Spain
2Department of Physiology, Northwestern University, Chicago, Illinois, 60611, USA
3IBM T.J. Watson Research Center, 1101 Kitchawan Rd., Yorktown Heights, New York 10598, USA

Received 13 January 2004; published 6 January 2005

Functional magnetic resonance imaging is used to extract functional networks connecting correlated human brain sites. Analysis of the resulting networks in different tasks shows that (a) the distribution of functional connections, and the probability of finding a link versus distance are both scale-free, (b) the characteristic path length is small and comparable with those of equivalent random networks, and (c) the clustering coefficient is orders of magnitude larger than those of equivalent random networks. All these properties, typical of scale-free small-world networks, reflect important functional information about brain states.


©2005 The American Physical Society

URL: http://link.aps.org/doi/10.1103/PhysRevLett.94.018102
DOI: 10.1103/PhysRevLett.94.018102
PACS: 87.18.Sn, 87.19.La, 89.75.Da, 89.75.Hc

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